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SPAK (Sterile 20/SPS1-related proline/alanine-rich kinase) is a protein kinase belonging to the mitogen-activated protein kinase (MAPK) superfamily that has been found to be extensively distributed across the body. The SPAK downstream substrates NKCC 1 and KCC 2 in the central nervous system are important in the interpretation of developmental mental disorders. The present study aimed...
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