The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
In this issue of Structure, Jin et al. (2007) report the structure of Schizosaccharomyces pombe AMPK embracing two moles of ADP by its γ subunit. This structure highlights the complexity of AMPK regulation across eukaryotes and challenges the regulatory dogma.
AMP-activated protein kinase (AMPK) coordinates cellular metabolism in response to energy demand as well as to a variety of stimuli. The AMPK β subunit acts as a scaffold for the α catalytic and γ regulatory subunits and targets the AMPK heterotrimer to glycogen. We have determined the structure of the AMPK β glycogen binding domain in complex with β-cyclodextrin. The structure reveals a carbohydrate...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.