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The mitochondrion is especially complex and interesting because of its prokaryotic origins and subsequent integration into the eukaryotic cell and establishment as an essential organelle. As a result of this evolutionary history, the mitochondrion is a mix of “old and new” biology. For example, this organelle has maintained its own small genome that codes for a handful of inner membrane proteins and...
The mitochondrion has developed an elaborate translocation system for the import of nuclear-coded proteins and the export of proteins coded on the mitochondrial genome. Precursor proteins contain targeting and sorting information to reach the mitochondrion, while the translocons recognize the information and direct the pre-cursor to the correct compartment. The outer membrane contains the TOM (translocase...
The mitochondrion has developed an elaborate translocation system for the import of nuclear-coded proteins and the export of proteins coded on the mitochondrial genome. Precursor proteins contain targeting and sorting information to reach the mitochondrion, while the translocons recognize the information and direct the pre-cursor to the correct compartment. The outer membrane contains the TOM (translocase...
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