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The ventral medial prefrontal cortex (vmPFC) has long been implicated in monitoring of memory veracity, and more recently also in memory schema functions. In our model of strategic retrieval the two are related. We have proposed that the vmPFC has two schema-dependent functions: (i) to establish context-relevant templates against which the output of memory systems can be compared; (ii) to mediate...
The current ubiquity of functional neuroimaging studies, and the importance they have had in elucidating brain function, obscures the fact that much of what we know about brain–behavior relationships derives largely from the study of single‐ and multiple‐patient cases. A major goal of the present review is to describe how single cases continue to uniquely and critically contribute to cognitive neuroscience...
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