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Microglia polarization is associated with the pathogenesis of depression. A previous study shows that long non‐coding RNA uc.80‐ is down‐regulated in the hippocampus of depressed rats. Thus, this article aims to investigate the role of uc.80‐ in microglia polarization in depression. We first established depression model rats by chronic unpredictable mild stress (CUMS) regiment. We found that hippocampus...
wMania and depression in bipolar disorder (BP) manifest two extremes of aberrant emotional, physiologic and behavioral arousal states despite similarities in treatment response and neurocognitive deficits. We used resting-state functional magnetic resonance imaging (rsfMRI) to explore the common and unique abnormal functional connectivity underlying acute manic or depressed state in BP.18 Patients...
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