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Abstract. Given all known biological activities, it is anticipated that transforming growth factors beta (TGF-s) play important roles in many different developmental processes. As all three TGF- isoforms display overlapping expression patterns, deletion of one TGF- isoform might be compensated for by another. In the present study, targeted disruption of both Tgf2 and Tgf3 genes was undertaken to circumvent...
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