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To assess the mechanism of long-term LDL-C-lowering effect of ezetimibe-plus-statin.Coronary artery disease patients whose LDL-C ≥70 mg/dL after treatment with atorvastatin 10 mg/day or rosuvastatin 2.5 mg/day were randomly assigned to receive ezetimibe 10 mg/day + statin (n = 78) or double-dose statin (n = 72) for 52 weeks.Greater LDL-C reduction was observed and maintained until 52 weeks in ezetimibe-plus-statin,...
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