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Tasty high-fat and high-sugar foods induce overeating and obesity in animals. To separate the roles of oral and postoral factors in food preference and consumption, recent studies have used an ''electronic esophagus'' preparation. With this system, when an animal drinks a flavored solution, it controls the infusion of nutrients directly into its stomach through an implanted catheter. Improving the...
This study determined the feasibility of conditioning flavor preferences in mice by self-administered intragastric (IG) nutrient infusions. Male C57BL/6J mice were surgically fitted with an IG catheter that was attached by a tether system to an infusion pump. The mice were given ad-libitum access to chow and a flavored solution 23 h/day. Drinking was monitored with a computerized lickometer system...
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