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The metabonomic effects of hepatotoxic doses of pravastatin on the urinary metabolic profiles of female rats have been investigated using ultra performance liquid chromatography (UPLC)–oa-TOF-MS and, independently, by 1 H NMR spectroscopy. UPLC was performed using a 1mm microbore column packed with 1.7μm particles. Examination of the data obtained from the individual animals, aided by statistical...
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