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Three experiments are presented in which the neural and behavioral consequences of multiple ibotenic acid (IBO) injections into the hippocampus were examined in Sprague-Dawley rat pups. Rat pups were 11 or 15 days of age at the time of surgery (SURG11, SURG15), the dose of IBO was either 1 μg in 1 μl, 2.5 μg in 0.5 μl, or 5 μg in 1 μl for each of four injections, and pups were allowed to survive for...
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