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Major depressive disorder (MDD) shows increased coronary artery disease (CAD) risk of unknown mechanism(s). MDD is more common in women than men; CAD diagnosis can be difficult in women. Elevations of the inflammatory markers C-reactive protein (CRP) and serum amyloid A (SAA) predict increased CAD risk in populations; few data on these markers exist in MDD, particularly in remitted patients.We measured...
Cerebrospinal fluid (CSF) measures of β-amyloid 1–42 and tau are linked with the known neuropathology of Alzheimer’s disease (AD). Numerous lines of evidence have also suggested that individuals with at least one APOE ε4 allele on chromosome 19 are at increased risk of developing AD. We tested these CSF markers in groups of subjects with AD and healthy older control subjects, using the absence...
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