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The structure of Leukaemia Inhibitory Factor (LIF) and Oncostatin M (OSM) receptors is not completely resolved. Heterodimerization of gp190 and gp130 has been proposed to form a high af?nity receptor (type I) shared by LIF and OSM, while heterodimerization of gp130 with an as yet unidenti?ed subunit is proposed to form a high af?nity OSM receptor (type II) not shared by LIF. We have analysed the binding...
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