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The purpose of this study was to examine the effect of mineral trioxide aggregate (MTA) on pluripotent-mesenchymal cell differentiation.The pluripotent-mesenchymal cell line C2C12 was cultured in a 5% serum medium to induce cell differentiation with or without MTA. The differentiation to myoblasts was analyzed by the immunocytochemical staining of myosin heavy chains. The cellular phenotype-specific...
We examined the effect of β-alanyl-L-histidinato zinc (AHZ) on the differentiation of human periodontal ligament (HPDL) cells. HPDL cells were cultured with α-minimum essential medium containing 10% fetal bovine serum with or without 10 -4 or 10 -5 M AHZ for up to 10 days. The expression of runt-related transcription factor-2/core binding factor α-1 (RUNX2/Cbfa1), Sox9, bone...
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