The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The stereo- and enantioselective synthesis of clavulones 6 and their analogues 48 is described. γ-Hydroxycyclopentenones (-)-13 and 44, which are key intermediates in this approach, are obtained from enantiopure endo-tricyclo[5.2.1.0 2,6 ]decadienones (+)-14 and (+)-20 in 6 and 8 steps, respectively. Crucial steps are the reductive epoxy ring opening in compounds (+)-25 and 39...
A convenient total synthesis of chromomoric acid B methyl ester 1 and the first synthesis of chromomoric acid F methyl ester 2 have been described. A one-pot Michael addition-enolate trapping sequence afforded ketone 5 which after a few steps was converted to 1. Retro Diels-Alder reaction of ester 7 afforded enone 9 which was then transformed to the target molecule 2 through hydrogenation and α-hydroxylation.
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.