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To investigate the effect of hyperbaric oxygen (HBO) on platelet physiology.Human platelets were exposed to HBO (97.7% O 2 , balance CO 2 at 2.2 ata) or control (CON; 5% CO 2 , balance air at 1 ata) for 90 min, and analyzed for aggregation, protein release, NO production, and activation.HBO induced 29.8±3.0% of platelets to aggregate compared with CON (5.5±0.9%). Proteins observed...
The aim of the study was to investigate whether a single hyperbaric oxygen exposure causes oxidative stress in isolated platelets.Isolated horse platelets were exposed to 100% oxygen at 2.2 atmospheres, or 100% oxygen under normobaric conditions, or air under normobaric conditions for 90 min.There were no differences in platelet SOD activity between conditions, but there was a rise in SOD in all cases...
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