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Nonivamide (NVA) and sodium nonivamide acetate (SNA) are both synthetic analogues of capsaicin. In this present study, the in vivo skin erythema test and non-invasive surface recovery techniques were performed in humans for capsaicin, NVA and SNA after transdermal ointment application. In order to quantify the skin erythema and irritation caused by capsaicin and its analogues, laser Doppler flowmetry...
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