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Suanzaorenhehuan Formula (SHF) has been used for treating depression-like disorders for many years in China. The saponins part of the SHF (SSHF) extract was the antidepressant effective component.To investigate the antidepressant-like effect of SSHF and its possible mechanisms.Experimental approaches including the forced swim test (FST), the tail suspension test (TST) and unpredictable chronic mild...
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