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There is an increasing interest in using N‐acetylcysteine (NAC) as a treatment for neurodegenerative disorders to increase glutathione (GSH) levels and its redox status. The purpose of this study was to characterize the biosynthesis of NAC to GSH using a novel stable isotope‐labeled technique, and investigate the pharmacodynamics of NACin vivo. Female wild‐type mice were given a single intravenous...
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