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Blood plasma heat capacity profiles of lung cancer patients were recorded by DSC and monitored during a first-line chemotherapy cycle including four sessions of treatment by a platinum-based doublet of cisplatin or carboplatin in combination with a third-generation agent (paclitaxel, gemcitabine, or docetaxel). The heat capacity profiles were deconvoluted into the major blood proteome constituent...
Differential scanning calorimetry (DSC) has been employed to examine the thermal behavior of brain tissues affected by a drug-induced neurodegenerative disorder. An animal (mouse) model of scopolamine-induced dementia was used. The DSC measurements performed on supernatants of brain tissue homogenates revealed large differences between the heat capacity profiles for healthy animals and for animals...
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