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The objective of this study was to predict Rb (blood/plasma ratio) in humans using a simple method. Human and rat Rb and free fraction in plasma (fp) values were obtained from the literature. The ratio of total red blood cell concentration to the free concentration in plasma (Kb) was calculated using fp and Rb. Four methods were used for the prediction of Rb: (A) use of rat Rb; (B) use of Rb calculated...
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