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In this paper, we introduced a signal-on electrochemical sensor based on target-induced split aptamer fragments conjunction. To construct the aptasensor, the sequence of the 15-base anti-thrombin DNA aptamer was split into two fragments, one of which was attached to a gold electrode via thiol self-assembled monolayer chemistry and the second of which was modified with the redox moiety ferrocene. Thrombin-induced...
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