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We applied high-performance liquid chromatography (HPLC) analysis for monoamine and monoamine metabolite concentrations in discrete brain regions micropunched from male rats. Rats were decapitated immediately after they had engaged in various components of sexual behavior or had simply spent an equivalent period in the testing chamber. We evaluated the effects of fluoxetine (10 mg/kg) on these measures...
The forced swim test (FST) is a widely used rodent model for screening antidepressants. The current study assessed neurochemical and immunological effects of the FST. Eighteen Sprague-Dawley rats were randomly divided into three groups: a Control Group with no swim, a Single Swim Group exposed to one swim, and a Double Swim Group with a second swim 24 hr after the first. The FST consisted of placing...
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