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Cytomegalovirus (CMV) induced autophagy affects virus replication and survival of the infected cells. The purpose of this study was to investigate the role of autophagy inhibition by 3‐methyladenine (3‐MA) on murine cytomegalovirus (MCMV) replication and whether it is associated with caspase‐3 dependent apoptosis. The eyecup isolated from adult C57BL/6J mice (6–8 weeks old) and mouse embryo fibroblast...
The purpose of this study was to determine whether autophagy regulates the expression of human cytomegalovirus (HCMV) immediately early two viral protein (IE2). Rapamycin and 3‐methyladenine (3‐MA) were used to stimulate or suppress autophagy during HCMV infection. UL122 recombinant plasmid was transfected to overexpress IE2 and small interference RNA against autophagy‐related protein 3 (ATG3) was...
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