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Enzymes contain several subunits to maintain different biological functions. However, it remains a great challenge for specific discrimination of one subunit over another. Toward this end, the fluorescent probe TPEMA is now presented for highly specific detection of the B subunit of cytosolic creatine (CK) kinase isoenzyme (CK‐B). Owing to its aggregation‐induced emission property, TPEMA shows highly...
Der Gel‐Sol‐Übergang eines Hydrogels, in dem ein Enzym eingeschlossen ist, kann effizient durch die Bindung eines Substrats gesteuert werden. Das freigesetzte Enzym kann anschließend als Katalysator wirken und das Signal verstärken (siehe Bild). Schon 20 ng Kokain lassen sich binnen 10 min anhand eines Farbumschlags mit bloßem Auge nachweisen.
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