Search results for: Tsai-Chung Li

Items from 1 to 20 out of 119 results

article

Increased plasma levels of monocyte chemoattractant protein‐1 in patients with hepatitis B virus pre‐S2 gene deletion mutation predict a higher risk of hepatocellular carcinoma recurrence after curative surgical resection

Long‐Bin Jeng, Tsai‐Chung Li, John Wang, Chiao‐Fang Teng

Cancer > 129 > 17 > 2621 - 2636

Background Despite resection surgery as a curative therapy for hepatocellular carcinoma (HCC), the high rate of postoperative HCC recurrence remains a big challenge for patient survival. Chronic hepatitis B virus (HBV) infection is the most important risk factor for HCC. Deletion mutation in the HBV pre‐S2 gene leads to expression of an essential viral oncoprotein called pre‐S2 mutant and represents...

article

Exploring the relationships among professional quality of life, personal quality of life and resignation in the nursing profession

Yen‐Chin Chen, Tsai‐Chung Li, Ya‐Wen Chang, Hui‐Chuan Liao, more

Journal of Advanced Nursing > 77 > 6 > 2689 - 2699

Aim To explore the relationships between nurses' quality of life, personal quality of life, intention to stay (ITS) and resign and factors related to resignation. Design Prospective cohort design. Methods The participants were recruited from three different levels of hospital in central Taiwan. The survey instruments were structured questionnaires including demographics, Professional Quality...

article

Mitochondrial DNA haplogroups affect physical performances in Han older adults: an 8‐year follow‐up prospective cohort study

Chuan‐Wei Yang, Chia‐Ing Li, Jan‐Gowth Chang, Chiu‐Shong Liu, more

Geriatrics & Gerontology International > 21 > 2 > 166 - 171

Aim The objective of this study was to explore the association between mitochondrial DNA (mtDNA) haplogroups and physical performances in Han older adults. Methods This study was an 8‐year follow‐up prospective cohort study. A total of 104 Han older adults completed the measurements of the 6‐min walk test, grip strength and mitochondrial DNA sequencing. The mtDNA haplogroups were classified by...

article

Building clinical risk score systems for predicting the all‐cause and expanded cardiovascular‐specific mortality of patients with type 2 diabetes

Chiu‐Shong Liu, Chia‐Ing Li, Mu‐Cyun Wang, Sing‐Yu Yang, more

Diabetes, Obesity and Metabolism > 23 > 2 > 467 - 479

Aim To develop and validate risk score systems by examining the effects of glycaemic and blood pressure variabilities on the all‐cause and expanded cardiovascular‐specific mortality of people with type 2 diabetes. Materials and methods This retrospective cohort study consisted of 9692 patients aged 30‐85 years, diagnosed with type 2 diabetes and enrolled in a managed care programme of a medical...

article

Relationship among urinary advanced glycation‐end products, skeletal muscle mass and physical performance in community‐dwelling older adults

Chuan‐Wei Yang, Chia‐Ing Li, Chiu‐Shong Liu, Chih‐Hsueh Lin, more

Geriatrics & Gerontology International > 19 > 10 > 1017 - 1022

Aim Advanced glycation end‐products are important factors in muscle function and physical performance among older adults. However, the association between sarcopenia and urinary carboxymethyl‐lysine (uCML) levels remains unclear. The present study aimed to investigate the relationship among uCML levels, skeletal muscle mass, physical performance and sarcopenia among community‐dwelling older adults...

article

The effectiveness of a clinical reasoning teaching workshop on clinical teaching ability in nurse preceptors

Hui‐Chuan Liao, Yih‐Ming Yang, Tsai‐Chung Li, Jui‐Fen Cheng, more

Journal of Nursing Management > 27 > 5 > 1047 - 1054

Aim To explore the effectiveness of a clinical reasoning teaching workshop (CRTW) in preceptors' teaching ability, self‐efficacy of clinical reasoning teaching. Background Preceptors' teaching skills are crucial for training novice nurses. How to enhance preceptors' teaching ability is a pertinent concern in clinical practice. Methods This study comprised two stages. At stage I, we administered...

article

Frailty, transition in frailty status and all-cause mortality in older adults of a Taichung community-based population

Mu-Cyun Wang, Tsai-Chung Li, Chia-Ing Li, Chiu-Shong Liu, more

BMC Geriatrics > 2019 > 19 > 1 > 1-8

Background Previous studies have reported the associations of frailty phenotype or its components with mortality. However, studies that explored the effects of transition in frailty status on mortality were far less in Asian or Chinese. The aim of this study was to evaluate baseline frailty status and one-year change of frailty status in relation to all-cause mortality in Taiwanese community-dwelling...

article

A qualitative study of attitudes to and perceptions of betel quid consumption and its oral health implications in Taiwan

Irene Tamí‐Maury, Wei‐Fen Ma, Mi‐Ting Lin, Cheng‐Chieh Lin, more

Community Dentistry and Oral Epidemiology > 47 > 1 > 58 - 64

Objectives Betel quid (BQ) chewing is extremely prominent in South and Southeast Asia because it considered by users to be of social, cultural and religious importance. BQ chewing has been recognized as a risk factor for oral premalignant lesions and oral cancer. Because BQ chewing has become a severe health risk in Taiwan, the development of prevention and cessation programmes is essential. The...

article

Development and validation of prediction models for the risks of diabetes-related hospitalization and in-hospital mortality in patients with type 2 diabetes

Tsai-Chung Li, Chia-Ing Li, Chiu-Shong Liu, Wen-Yuan Lin, more

Metabolism > 2018 > 85 > C > 38-47

Diabetes is a major cause of hospitalization and in-hospital mortality. However, a scoring system that can be used to identify diabetic patients at risk of diabetes-related hospitalization and in-hospital mortality is lacking.We included 32,653 patients in this retrospective cohort study. All recruited patients had type 2 diabetes, were 30–84 years of age, and were enrolled in the National Diabetes...

article

Three-year renal function trajectory and its association with adverse renal event in patients with type 2 diabetes

Tsai-Chung Li, Tzu-Yun Yu, Chia-Ing Li, Chiu-Shong Liu, more

Journal of Diabetes and its Complications > 2018 > 32 > 8 > 784-790

The study evaluated associations between 3-year eGFR trajectory patterns and adverse renal event in diabetic patients.Adverse renal event was defined as sustained eGFR <60 or one ACR >300 mg/g creatinine. Cox proportional hazards models evaluated association between eGFR trajectory patterns and adverse renal event.We detected six clusters. Cluster 1 had a stable but relatively low baseline eGFR...

article

Bitter melon seed oil increases mitochondrial content in gastrocnemius muscle and improves running endurance in sedentary C57BL/6J mice

Fei Koon Chan, Chin Hsu, Tsai-Chung Li, Wen-Hung Chen, more

The Journal of Nutritional Biochemistry > 2018 > 58 > C > 150-157

The α-eleostearic acid (α-ESA) in bitter melon seed oil (BMSO) is efficiently converted by the body into rumenic acid. The objective of this study was to investigate effects of BMSO on skeletal muscle fiber-type switch and endurance capacity in mice, with or without exercise training. In a 3×2 factorial design, C57BL/6J mice were fed a 30% high-fat diet composed of soybean oil, butter or a 1:1 mixture...

article

The effectiveness of learning portfolios in learning participation and learners’ perceptions of skills and confidence in the mother of preterm infant

Yi-Chuan Cheng, Li-Li Chen, Yu-Shan Chang, Tsai-Chung Li, more

Midwifery > 2018 > 62 > C > 86-91

The purpose of this study was to investigate the effectiveness of preterm infant learning portfolios in enabling mothers to develop infant care knowledge and skills, as well as confidence in their abilities. This study used a quasi-experimental design. The sample consisted of 52 mothers with preterm infants recruited at a neonatal intermediate unit of a medical centre in central Taiwan. Among those,...

article

The effectiveness of Culturally Sensitive Collaborative Treatment of depressed Chinese in family medicine clinics: A randomized controlled trial

Hui-Chun Huang, Shen-Ing Liu, Lee-Ching Hwang, Fang-Ju Sun, more

General Hospital Psychiatry > 2018 > 50 > C > 96-103

To investigate whether the Culturally Sensitive Collaborative Treatment (CSCT) would improve outcomes for patients with major depression who were managed in family medicine clinics in Taiwan.A single-blinded randomized trial was conducted in 26 family medicine clinics. Patients with major depressive disorder were consecutively randomized to either CSCT or treatment as usual (TAU). The primary outcome...

article

Subject-enabled analytics model on measurement statistics in health risk expert system for public health informatics

Chi-Jung Chung, Yu-Chen Kuo, Yun-Yu Hsieh, Tsai-Chung Li, more

International Journal of Medical Informatics > 2017 > 107 > C > 18-29

This study applied open source technology to establish a subject-enabled analytics model that can enhance measurement statistics of case studies with the public health data in cloud computing.The infrastructure of the proposed model comprises three domains: 1) the health measurement data warehouse (HMDW) for the case study repository, 2) the self-developed modules of online health risk information...

article

Clinical efficacy and IL-17 targeting mechanism of Indigo naturalis as a topical agent in moderate psoriasis

Hui-Man Cheng, Yang-Chang Wu, Qingmin Wang, Michael Song, more

BMC Complementary and Alternative Medicine > 2017 > 17 > 1 > 1-11

Background Indigo naturalis is a Traditional Chinese Medicine (TCM) ingredient long-recognized as a therapy for several inflammatory conditions, including psoriasis. However, its mechanism is unknown due to lack of knowledge about the responsible chemical entity. We took a different approach to this challenge by investigating the molecular profile of Indigo naturalis treatment and impacted pathways...

article

The joint association of insulin sensitivity and physical activity on the skeletal muscle mass and performance in community-dwelling older adults

Chuan-Wei Yang, Chia-Ing Li, Tsai-Chung Li, Chiu-Shong Liu, more

Experimental Gerontology > 2017 > 95 > C > 34-38

Many well-known risk factors that may lead to sarcopenia are already discovered. However, their combined effects on sarcopenia components remain unclear. This study aims to explore the joint association of physical activity and insulin sensitivity on skeletal muscle mass and performance of Taiwanese elder people from a metropolitan community.The study sample involved 844 elders who were examined through...

article

Traditional Chinese medicine as adjunctive therapy improves the long-term survival of lung cancer patients

Yueh-Hsiang Liao, Chia-Ing Li, Cheng-Chieh Lin, Jaung-Geng Lin, more

Journal of Cancer Research and Clinical Oncology > 2017 > 143 > 12 > 2425-2435

Purpose Traditional Chinese medicine is one of the popular alternative treatments for cancer, mainly enhancing host immune response and reducing adverse effect of chemotherapy. This study first explored traditional Chinese medicine treatment effect on long-term survival of lung cancer patients. Methods This study evaluated whether traditional Chinese medicine combined with conventional cancer treatment...

article

Transformation of 5-D itch scale and numerical rating scale in chronic hemodialysis patients

Jia-Wen Lai, Hung-Chih Chen, Che-Yi Chou, Hung-Rong Yen, more

BMC Nephrology > 2017 > 18 > 1 > 1-5

Background Pruritus is a common and frustrating symptom in hemodialysis (HD) patients and 5-D itch scale is proposed as a reliable measurement of pruritus. However, information regarding 5-D itch scale categories is currently unavailable. We explored optimal cut-offs 5-D itching scale based on numerical rating scale (NRS) categories in HD patients. Methods Four hundred and nine HD patients in China...

article

Qi deficiency is associated with depression in chronic hemodialysis patients

Yuan-Ching Liao, Che-Yi Chou, Chiz-Tzung Chang, Tsai-Chung Li, more

Complementary Therapies in Medicine > 2017 > 30 > C > 102-106

Depression is a common bio-psycho-social problem in hemodialysis (HD) patients. Traditional Chinese medicine has been used for symptom management in patients with depression. Identification of the specific constitution in traditional Chinese medicine is critical for personalized care. However, the association between depression and specific constitution in HD patients is unknown.We conducted a cross-sectional...

article

Hypoglycemic effects of Trichosanthes kirilowii and its protein constituent in diabetic mice: the involvement of insulin receptor pathway

Hsin-Yi Lo, Tsai-Chung Li, Tse-Yen Yang, Chia-Cheng Li, more

BMC Complementary and Alternative Medicine > 2017 > 17 > 1 > 1-9

Background Diabetes is a serious chronic metabolic disorder. Trichosanthes kirilowii Maxim. (TK) is traditionally used for the treatment of diabetes in traditional Chinese medicine (TCM). However, the clinical application of TK on diabetic patients and the hypoglycemic efficacies of TK are still unclear. Methods A retrospective cohort study was conducted to analyze the usage of Chinese herbs in...

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INFONA - science communication portal

Search results for: Tsai-Chung Li

Increased plasma levels of monocyte chemoattractant protein‐1 in patients with hepatitis B virus pre‐S2 gene deletion mutation predict a higher risk of hepatocellular carcinoma recurrence after curative surgical resection

Exploring the relationships among professional quality of life, personal quality of life and resignation in the nursing profession

Mitochondrial DNA haplogroups affect physical performances in Han older adults: an 8‐year follow‐up prospective cohort study

Building clinical risk score systems for predicting the all‐cause and expanded cardiovascular‐specific mortality of patients with type 2 diabetes

Relationship among urinary advanced glycation‐end products, skeletal muscle mass and physical performance in community‐dwelling older adults

The effectiveness of a clinical reasoning teaching workshop on clinical teaching ability in nurse preceptors

Frailty, transition in frailty status and all-cause mortality in older adults of a Taichung community-based population

A qualitative study of attitudes to and perceptions of betel quid consumption and its oral health implications in Taiwan

Development and validation of prediction models for the risks of diabetes-related hospitalization and in-hospital mortality in patients with type 2 diabetes

Three-year renal function trajectory and its association with adverse renal event in patients with type 2 diabetes

Bitter melon seed oil increases mitochondrial content in gastrocnemius muscle and improves running endurance in sedentary C57BL/6J mice

The effectiveness of learning portfolios in learning participation and learners’ perceptions of skills and confidence in the mother of preterm infant

The effectiveness of Culturally Sensitive Collaborative Treatment of depressed Chinese in family medicine clinics: A randomized controlled trial

Subject-enabled analytics model on measurement statistics in health risk expert system for public health informatics

Clinical efficacy and IL-17 targeting mechanism of Indigo naturalis as a topical agent in moderate psoriasis

The joint association of insulin sensitivity and physical activity on the skeletal muscle mass and performance in community-dwelling older adults

Traditional Chinese medicine as adjunctive therapy improves the long-term survival of lung cancer patients

Transformation of 5-D itch scale and numerical rating scale in chronic hemodialysis patients

Qi deficiency is associated with depression in chronic hemodialysis patients

Hypoglycemic effects of Trichosanthes kirilowii and its protein constituent in diabetic mice: the involvement of insulin receptor pathway

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