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To develop a consensus guideline for craniospinal target volume (TV) delineation in children and young adults participating in SIOPE studies in the era of high-precision radiotherapy.During four consensus meetings (Cambridge, Essen, Liverpool, and Marseille), conventional field-based TV has been translated into image-guided high-precision craniospinal TV by a group of expert paediatric radiation oncologists...
To review the published clinical data on non-small cell lung cancer treated with radical radiotherapy to confirm a dose–response relationship as a basis for further dose-escalation trials.Twenty-four published clinical trials were identified, 16 of which – with 29 different standard, hyper- and hypofractionated treatment schedules – were analysed. Prescription doses were converted to biologically-equivalent...
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