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To investigate the role of S100 calcium‐binding protein A16 (S100A16) in hepatic lipid metabolism, S100a16 transgenic, S100a16 knockdown, and wildtype C57BL/6 mice were fed either a high‐fat diet (HFD) or normal‐fat diet (NFD) for 16 weeks. The results showed that for HFD‐fed mice, S100a16 transgenic mice showed significantly more severe fatty liver than other HFD‐fed mice, with a significant increase...
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