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Phytochemical investigation of the rhizomes of Smilax trinervula led to isolation and structure elucidation of eight lignan glycosides, including five new lignans, namely, (7S, 8R, 8′R)-4, 4′, 9-trihydroxy-3, 3′, 5, 5′-tetramethoxy-7, 9′-epoxylignan-7′-one 4′-O-β-d-glucopyranoside (1), (7S, 8R, 8′R)-4, 4′, 9-trihydroxy-3, 3′, 5, 5′-tetramethoxy-7, 9′-epoxylignan-7′-one 4-O-β-d- glucopyranoside (2)...
Three new steroidal saponins, namely, trinervulosides A–C (1–3), were isolated from the rhizomes and roots of Smilax trinervula, together with four known compounds, 4–7. Their structures were determined through chemical evidence, NMR spectroscopy, mass spectrometry and comparison with the literature. Compounds 1–7 were assayed for cytotoxic activities, and only trinervuloside B (2) showed activity...
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