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The purpose of the study was to evaluate the effect of long-term β1-aderergic receptor (AR) blockade on left ventricular (LV) remodeling and function in patients with chronic, isolated, degenerative mitral regurgitation (MR).Isolated MR currently has no proven therapy that attenuates LV remodeling or preserves systolic function.Thirty-eight asymptomatic subjects with moderate to severe, isolated MR...
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