Search results for: Hiroshi Okada

Items from 1 to 20 out of 256 results

article

The transition of metabolic phenotypes and cardiovascular events: Panasonic cohort study 16

Takahiro Ichikawa, Hiroshi Okada, Masahide Hamaguchi, Norihiro Nishioka, more

Obesity > 32 > 5 > 999 - 1008

Objective The study objective was to investigate whether changes in metabolic phenotype affect the risk of cardiovascular events. Methods All 117,589 participants were included in this retrospective cohort study. The metabolic phenotypes of the participants were assessed at two points (the second evaluation was set 2 years after the first evaluation), and the incidence rate of cardiovascular events...

article

Impact of an online nutrition management application service on glycaemic management in individuals with diabetes: A propensity‐score‐matched retrospective cohort study

Junya Hironaka, Hiroshi Okada, Megumi Minamida, Yuriko Kondo, more

Diabetes, Obesity and Metabolism > 26 > 5 > 1757 - 1765

Aims To assess the impact of ‘Oishi Kenko’, a nutrition management application (app), on glycaemic control in patients with diabetes. Materials and Methods A propensity‐score‐matched retrospective cohort study was performed using data from the KAMOGAWA‐DM cohort study conducted between January and June 2022 in Japan. We analysed data from patients with type 1 and type 2 diabetes, comparing users...

article

Effects of weight loss on metabolic dysfunction‐associated fatty liver disease in Japanese people: Non‐alcoholic fatty liver disease in the Gifu area, longitudinal analysis study

Yuka Hasegawa, Hiroshi Okada, Hanako Nakajima, Nobuko Kitagawa, more

Hepatology Research > 54 > 4 > 336 - 346

Aim Metabolic dysfunction‐associated fatty liver disease (MAFLD) is a major health concern. This cohort study aimed to evaluate the association between weight loss and remission of MAFLD in the Japanese population to aid the development of efficient treatment strategies. Methods This retrospective cohort study was conducted at a Japanese health screening center. Participants included 3309 individuals...

article

Testicular sperm retrieval in hemodialysis patients with anejaculation

Akiyoshi Osaka, Toshiyuki Iwahata, Ippei Hiramatsu, Hiroshi Okada, more

International Journal of Urology > 31 > 2 > 182 - 184

article

Younger patients and low c‐peptide immunoreactivity index but not nutritional states affect fasting blood ketone levels in Japanese with type 1 diabetes after sodium‐glucose cotransporter 2 inhibitor administration

Hanako Nakajima, Hiroshi Okada, Yuta Yoshimura, Toru Tanaka, more

Diabetes, Obesity and Metabolism > 25 > 12 > 3682 - 3689

Aim Sodium‐glucose cotransporter 2 inhibitors (SGLT2is) are available for individuals with type 1 diabetes, but appropriate use is recommended to prevent ketosis or ketoacidosis. This study aimed to evaluate the risk of ketosis in people with type 1 diabetes, focusing on the relationship between nutritional assessment, glycaemic status, c‐peptide immunoreactivity (CPR) index and body composition...

article

Preoperative testosterone and follicle stimulating hormone levels are important predictors for sperm retrieval by microdissection testicular sperm extraction in non‐mosaic Klinefelter syndrome

Kei‐ichiro Uemura, Toshiyuki Iwahata, Hisamitsu Ide, Akiyoshi Osaka, more

Andrologia > 54 > 11 > n/a - n/a

This study aimed to assess outcomes of microdissection testicular sperm extraction (MD‐TESE) and identify predictors for sperm retrieval (SR) in patients with non‐mosaic Klinefelter syndrome (NM‐KFS). We retrospectively evaluated 37 patients with NM‐KFS who underwent MD‐TESE. Data of age at operation, body mass index (BMI), testicular volume, serum luteinizing hormone (LH), follicle stimulating hormone...

article

Metabolic phenotypes and incident type 2 diabetes: Population‐based Panasonic cohort study 6

Ayaka Kobayashi, Hiroshi Okada, Masahide Hamaguchi, Kazushiro Kurogi, more

Obesity > 30 > 11 > 2286 - 2293

Objective This study aimed to assess the association between changes in metabolic phenotypes and incident type 2 diabetes. Methods This retrospective cohort study included participants from a medical health checkup program conducted by the Panasonic Corporation, Japan, between 2008 and 2018. The metabolic phenotypes of the participants in 2008 and 2013 were assessed. The association between changes...

article

Low aspartate aminotransferase/alanine aminotransferase ratio is a predictor of diabetes incidence in Japanese people: Population‐based Panasonic cohort study 5

Hanako Nakajima, Hiroshi Okada, Masahide Hamaguchi, Kazushiro Kurogi, more

Diabetes/Metabolism Research and Reviews > 38 > 6 > n/a - n/a

Aims The aim of this study was to calculate the cut‐off values of liver enzymes to identify the risk of incident type 2 diabetes (DM) and to investigate the association between liver enzymes and incident DM in participants with or without obesity. Materials and Methods The long‐term cohort study included 70,688 subjects who underwent medical health checkups in 2008. The cut‐off values of alanine...

article

Implementation of balancing domain decomposition method for parallel finite element analysis involving inactive elements

Yasunori Yusa, Hiroaki Kobayashi, Yuma Murakami, Hiroshi Okada

International Journal for Numerical Methods in Engineering > 123 > 17 > 3974 - 4000

The present study developed a numerical method to implement domain decomposition (DD) solvers with the diagonal‐scaling preconditioner, the balancing domain decomposition (BDD) preconditioner and the BDD with diagonal scaling (BDD‐DIAG) preconditioner, for inactive elements. The inactive element, which is a finite element having zero stiffness, is used in several fields such as multi‐pass welding...

article

SARS‐CoV‐2 infection and venous thromboembolism after surgery: an international prospective cohort study

COVIDSurg Collaborative, GlobalSurg Collaborative, Dmitri Nepogodiev, Joana FF Simoes, more

Anaesthesia > 77 > 1 > 28 - 39

SARS‐CoV‐2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri‐operative or prior SARS‐CoV‐2 were at further increased risk of venous thromboembolism. We conducted a planned sub‐study and analysis from...

article

Does mirabegron deteriorate spermatogenesis? A lesson from spinal cord injury cases

Hiroshi Okada, Tadahiko Tokumoto, Akiyoshi Osaka, Takashi Tanaka, more

LUTS: Lower Urinary Tract Symptoms > 13 > 4 > 435 - 439

Objectives To evaluate whether the long‐term usage of mirabegron, which was reported to have potential side effects on male reproductive organs in animal studies, was harmful to spermatogenesis in human testis. Methods Thirty consecutive patients with spinal cord injury (20‐48 years old) who performed clean intermittent catheterization were involved in this study. Ten patients were treated with...

article

Effects of pre‐operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study

COVIDSurg Collaborative, GlobalSurg Collaborative, Dmitri Nepogodiev, Joana FF Simoes, more

Anaesthesia > 76 > 11 > 1454 - 1464

We aimed to determine the impact of pre‐operative isolation on postoperative pulmonary complications after elective surgery during the global SARS‐CoV‐2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors...

article

Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study

COVIDSurg Collaborative, GlobalSurg Collaborative, Dmitri Nepogodiev, Joana FF Simoes, more

Anaesthesia > 76 > 6 > 748 - 758

Peri‐operative SARS‐CoV‐2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS‐CoV‐2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre‐operative SARS‐CoV‐2 infection...

article

Developing and testing a set of quality indicators for pharmacist home visit services: A mixed methods study in Japan

Kenji Fujita, Kazuki Kushida, Hiroshi Okada, Rebekah J. Moles, more

British Journal of Clinical Pharmacology > 87 > 4 > 1940 - 1952

Objective Quality indicators (QIs) are an important mechanism by which health services can be evaluated. We aimed to develop a set of QIs for pharmacist home visit services and assess their measurement properties. Methods A three‐step procedure was applied: (1) Selection of existing content‐validated QIs from the international literature and the development of QIs based on national guidelines and...

article

GaN‐Based Monolithic Inverter Consisting of Enhancement‐ and Depletion‐Mode MOSFETs by Si Ion Implantation

Hiroshi Okada, Kiyomasa Miwa, Taichi Yokoyama, Keisuke Yamane, more

physica status solidi (a) > 217 > 3 > n/a - n/a

Herein, the effects of Si ion implantation on GaN in a dose range of 10¹¹–10¹⁴ cm⁻² towards a GaN‐based monolithic inverter circuit consisting of n‐channel enhancement‐ and depletion‐mode MOSFETs (E‐MOSFET and D‐MOSFET) are investigated. The implantation dose dependence is investigated by capacitance–voltage (C–V) measurement of Si‐implanted GaN metal–oxide–semiconductor (MOS) capacitors. Enhanced...

article

Relationship between nonalcoholic fatty liver disease and muscle quality as well as quantity evaluated by computed tomography

Muhei Tanaka, Hiroshi Okada, Yoshitaka Hashimoto, Muneaki Kumagai, more

Liver International > 40 > 1 > 120 - 130

Background & Aims Sarcopenia is reported to be associated with nonalcoholic fatty liver disease (NAFLD). Evaluation of skeletal muscle attenuation and area by computed tomography (CT) may represent a promising approach for evaluation of the risk of NAFLD. We examined the association between skeletal muscle characteristics and NAFLD and investigated the combined effect of these parameters on the...

article

The change in pharmacists’ attitude, confidence and job satisfaction following participation in a novel hypertension support service

Masaki Shoji, Mitsuko Onda, Hiroshi Okada, Naoki Sakane, more

International Journal of Pharmacy Practice > 27 > 6 > 520 - 527

Objectives To demonstrate how the confidence, attitude and job satisfaction of pharmacists who provide interventions and lifestyle support services to patients with hypertension are altered. Methods This study was a before‐and‐after study that used data from 50 pharmacists who participated in the Community Pharmacists Assist for Blood Pressure (COMPASS‐BP) study, which was an interventional study...

article

Mindset modification of community pharmacists in a collaborative relationship between a major hospital and neighboring community pharmacies: a qualitative study

Miwa Hinata, Kikuko Miyazaki, Hiroshi Okada, Takeo Nakayama

BMC Health Services Research > 2019 > 19 > 1 > 1-9

Background Patient information sharing between hospitals and community pharmacies is generally insufficient. Since August 2013, the pharmacy department of Kyoto University Hospital has initiated and mediated a collaborative relationship between physicians and neighboring community pharmacies (e.g., sharing outpatient blood test results, holding regular meetings among professionals, delivery of tracing...

article

Mechanochromism, Twisted/Folded Structure Determination, and Derivatization of (N‐Phenylfluorenylidene)acridane

Yutaka Matsuo, Ya Wang, Hiroshi Ueno, Takafumi Nakagawa, more

Angewandte Chemie International Edition > 58 > 26 > 8762 - 8767

(N‐Phenylfluorenylidene)acridane (Ph‐FA) compounds with electron‐withdrawing and ‐donating substituents (H, MeO, Ph, NO₂, Br, F) at the para position of the phenyl group were successfully synthesized by Barton–Kellogg reactions of N‐aryl thioacridones and diazofluorene. By using the substituent on the nitrogen atom to alter the electronic properties, both the folded and twisted conformers of p‐NO₂...

article

Mechanochromism, Twisted/Folded Structure Determination, and Derivatization of (N‐Phenylfluorenylidene)acridane

Yutaka Matsuo, Ya Wang, Hiroshi Ueno, Takafumi Nakagawa, more

Angewandte Chemie > 131 > 26 > 8854 - 8859

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INFONA - science communication portal

Search results for: Hiroshi Okada

The transition of metabolic phenotypes and cardiovascular events: Panasonic cohort study 16

Impact of an online nutrition management application service on glycaemic management in individuals with diabetes: A propensity‐score‐matched retrospective cohort study

Effects of weight loss on metabolic dysfunction‐associated fatty liver disease in Japanese people: Non‐alcoholic fatty liver disease in the Gifu area, longitudinal analysis study

Testicular sperm retrieval in hemodialysis patients with anejaculation

Younger patients and low c‐peptide immunoreactivity index but not nutritional states affect fasting blood ketone levels in Japanese with type 1 diabetes after sodium‐glucose cotransporter 2 inhibitor administration

Preoperative testosterone and follicle stimulating hormone levels are important predictors for sperm retrieval by microdissection testicular sperm extraction in non‐mosaic Klinefelter syndrome

Metabolic phenotypes and incident type 2 diabetes: Population‐based Panasonic cohort study 6

Low aspartate aminotransferase/alanine aminotransferase ratio is a predictor of diabetes incidence in Japanese people: Population‐based Panasonic cohort study 5

Implementation of balancing domain decomposition method for parallel finite element analysis involving inactive elements

SARS‐CoV‐2 infection and venous thromboembolism after surgery: an international prospective cohort study

Does mirabegron deteriorate spermatogenesis? A lesson from spinal cord injury cases

Effects of pre‐operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study

Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study

Developing and testing a set of quality indicators for pharmacist home visit services: A mixed methods study in Japan

GaN‐Based Monolithic Inverter Consisting of Enhancement‐ and Depletion‐Mode MOSFETs by Si Ion Implantation

Relationship between nonalcoholic fatty liver disease and muscle quality as well as quantity evaluated by computed tomography

The change in pharmacists’ attitude, confidence and job satisfaction following participation in a novel hypertension support service

Mindset modification of community pharmacists in a collaborative relationship between a major hospital and neighboring community pharmacies: a qualitative study

Mechanochromism, Twisted/Folded Structure Determination, and Derivatization of (N‐Phenylfluorenylidene)acridane

Mechanochromism, Twisted/Folded Structure Determination, and Derivatization of (N‐Phenylfluorenylidene)acridane

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