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As part of the National Cancer Institute's Drug Screening Program, a new class of antiretrovirals active against the human immunodeficiency virus HIV-1 has been identified, and the HIV-1 nucleocapsid protein NCp7 was proposed as the target of antiviral action. The 2,2 -dithiobis-[4 -(sulfamoyl)benzanilide] (3x) and the 2,2 -dithiobis(5-acetylamino)benzamide (10) represented the prototypic lead...
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