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Background. Currently, there is only limited information regarding tumor angiogenesis and its clinical implications in cases of esophageal carcinoma. The purpose of this study was to clarify which clinicopathologic parameters correlate with tumor angiogenesis; furthermore, the study was conducted to evaluate whether tumor angiogenesis is an independent prognostic factor in cases of esophageal carcinoma...
Background: We examined the prevalence, patterns, and clinical significance of nodal micrometastases in patients with esophageal cancer. Methods: Cervical, mediastinal, and abdominal lymph nodes systematically removed from 37 patients without conventional histologic evidence of lymph node metastasis from esophageal squamous cell carcinoma were immunohistochemically examined to detect cells that were...
Background: The purpose of the study was to determine whether extended radical esophagectomy is both clinically and oncologically indicated for patients with superficially invasive esophageal carcinomas. Methods: We reviewed 51 patients with this disease in whom extended radical esophagectomy was performed. Results: Major morbidity developed in 80% of the patients associated with no mortality after...
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