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90 Yttrium (Therasphere) microspheres administered via hepatic artery are a valuable option for treatment of hepatocellular carcinoma. This therapy targets tumor nodules while largely sparing hepatic parenchyma. This retrospective study examines liver explants from 13 adult patients with hepatocellular carcinoma who received intrahepatic Theraspheres and subsequently underwent liver transplantation...
We examined stage T1 to T4 hepatocellular carcinomas (HCC) to determine whether transforming growth factor alpha (TGFα) presence differed between early- and late-stage HCC and between tumors with low and high proliferative rates. Paraffin sections from 36 HCC were evaluated for TGFα and the proliferation markers Kiel 67 antigen (Ki67) or proliferating cell nuclear antigen (PCNA) by immunoperoxidase...
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