Search results for: Dae-Hyun Kim

Items from 1 to 20 out of 403 results

article

Nano/microgroove zirconium‐doped lanthanum oxide film with self‐aligned molecules for liquid crystal device application

Bo‐Kyeong Choi, Jin Young Oh, Dae‐Hyun Kim, Dong Wook Lee, more

Surface and Interface Analysis > 56 > 10 > 743 - 750

Herein, we propose a brush‐coated zirconium‐doped lanthanum oxide (ZrLaO) film as a liquid crystal (LC) alignment layer. The film‐curing temperature was adjusted to 70, 150, and 230°C. Polarized optical microscopy and pre‐tilt angle analysis confirmed that there was uniform and homogeneous LC alignment on the 230°C cured ZrLaO film. Atomic force microscopy revealed that the surface had a nano/microgroove...

article

Use of chronic care management service among Medicare beneficiaries in 2015–2019

Jieun Jang, Ellen P. McCarthy, Brianne Olivieri‐Mui, Sandra M. Shi, more

Journal of the American Geriatrics Society > 72 > 9 > 2730 - 2737

Background The Centers for Medicare and Medicaid Services (CMS) introduced chronic care management (CCM) services in 2015 for patients with multiple chronic diseases. Few studies examine the utilization of CCM services by geographic region, sociodemographic, and clinical characteristics. Methods We used 2014–2019 Medicare claims data from a 5% random sample of fee‐for‐service beneficiaries aged...

article

Artificial Vasa‐Vasorum Serves as an On‐Site Regenerative Promoter of Cell‐Free Vascular Grafting

Hyun‐su Ha, Sewoom Baek, Kyubae Lee, Sungwoo Cho, more

Advanced Functional Materials > 34 > 30 > n/a - n/a

The control paradigm of small vessel pathophysiology has changed to focus on the vascular out‐wall rather than the lumen‐intimal factors. As an emerging controller of the external wall, the microvasculature (“vasa vasorum”) provides interactional routes between the in‐and out‐sides of the vascular wall. Despite numerous approaches to developing small‐diameter vascular grafts, engineering artificial...

article

Impact of peri‐operative frailty and operative stress on post‐discharge mortality, readmission and days at home in Medicare beneficiaries

Chan Mi Park, Jessica J. Lie, Laiji Yang, Zara Cooper, more

Anaesthesia > 79 > 8 > 829 - 838

Background Understanding how patients' frailty and the physiological stress of surgical procedures affect postoperative outcomes may inform risk stratification of older patients undergoing surgery. The objective of the study was to examine the association of peri‐operative frailty with mortality, 30‐day readmission and days at home after non‐cardiac surgical procedures of different physiological...

article

Comparative safety and cardiovascular effectiveness of sodium‐glucose cotransporter‐2 inhibitors and glucagon‐like peptide‐1 receptor agonists in nursing homes

Melissa R. Riester, Andrew R. Zullo, Richa Joshi, Lori A. Daiello, more

Diabetes, Obesity and Metabolism > 26 > 8 > 3403 - 3417

Aim Studies examining the safety and effectiveness of sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) versus glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) among community‐dwelling adults may not generalize to nursing home (NH) residents, who are typically older and more multimorbid. We compared the safety and cardiovascular effectiveness of SGLT2is and GLP‐1RAs among US NH residents. ...

article

Utilization of transitional care management service among Medicare beneficiaries at high risk of readmission

Chan Mi Park, Ellen P. McCarthy, Sandra Shi, Brianne Olivieri‐Mui, more

Journal of the American Geriatrics Society > 72 > 7 > 2245 - 2248

article

Efficacy of Endovascular Thrombectomy in Acute Basilar Artery Occlusion with Low PC‐ASPECTS: A Nationwide Prospective Registry‐Based Study

Jun Young Chang, Ji Sung Lee, Wook‐Joo Kim, Jee Hyun Kwon, more

Annals of Neurology > 95 > 4 > 788 - 799

Objective We evaluated the efficacy of endovascular thrombectomy (EVT) on the functional outcome of patients with acute basilar artery occlusion and low posterior circulation acute stroke prognosis early computed tomography score (PC‐ASPECTS). Methods We identified patients with acute ischemic stroke due to basilar artery occlusion and PC‐ASPECTS of 6 or less, presenting within 24 h between August...

article

Trends in use of antipsychotics and psychoactive drugs in older patients after major surgery

Dae Hyun Kim, Hemin Lee, Ajinkya Pawar, Su Been Lee, more

Journal of the American Geriatrics Society > 71 > 12 > 3755 - 3767

Background Professional society guidelines recommend limiting the use of antipsychotics in older patients with postoperative delirium. How these recommendations affected the use of antipsychotics and other psychoactive drugs in the postoperative period has not been studied. Methods This retrospective cohort study included patients 65 years or older without psychiatric diagnoses who underwent major...

article

Construct validity of the electronic Veterans Affairs Frailty Index against clinician frailty assessment

Clark DuMontier, Robert Hennis, Cenk Yilidirim, Benjamin J. Seligman, more

Journal of the American Geriatrics Society > 71 > 12 > 3857 - 3864

Background Electronic frailty indices (eFIs) can expand measurement of frailty in research and practice and have demonstrated predictive validity in associations with clinical outcomes. However, their construct validity is less well studied. We aimed to assess the construct validity of the VA‐FI, an eFI developed for use in the U.S. Veterans Affairs Healthcare System. Methods Veterans who underwent...

article

Common non‐cardiovascular multimorbidity groupings and clinical outcomes in older adults with major cardiovascular disease

Stephanie Denise M. Sison, Kueiyu Joshua Lin, Mehdi Najafzadeh, Darae Ko, more

Journal of the American Geriatrics Society > 71 > 10 > 3179 - 3188

Background Among older adults, non‐cardiovascular multimorbidity often coexists with cardiovascular disease (CVD) but their clinical significance is uncertain. We identified common non‐cardiovascular comorbidity patterns and their association with clinical outcomes in Medicare fee‐for‐service beneficiaries with acute myocardial infarction (AMI), congestive heart failure (CHF), or atrial fibrillation...

article

A crosswalk of commonly used frailty scales

Stephanie Denise M. Sison, Sandra M. Shi, Kyung Moo Kim, Nessa Steinberg, more

Journal of the American Geriatrics Society > 71 > 10 > 3189 - 3198

Background Several validated scales have been developed to measure frailty, yet the direct relationship between these measures and their scores remains unknown. To bridge this gap, we created a crosswalk of the most commonly used frailty scales. Methods We used data from 7070 community‐dwelling older adults who participated in National Health and Aging Trends Study (NHATS) Round 5 to construct...

article

Frailty and uptake of angiotensin receptor neprilysin inhibitor for heart failure with reduced ejection fraction

Yu‐Chien Lee, Joshua K. Lin, Darae Ko, Susan Cheng, more

Journal of the American Geriatrics Society > 71 > 10 > 3110 - 3121

Background Frail older adults may be less likely to receive guideline‐directed medical therapy (GDMT)—renin‐angiotensin blockers, beta‐blockers, and mineralocorticoid receptor antagonists—for heart failure with reduced ejection fraction (HFrEF). We aimed to examine the uptake of angiotensin receptor neprilysin inhibitor (ARNI) and GDMT in frail older adults with HFrEF. Methods Using 2015–2019 Medicare...

article

The median doses of beta‐blockers among older adults with heart failure with reduced ejection fraction

Min Ji Kwak, Caroline Schaefer, Trudy Millard Krause, Parag Goyal, more

Journal of the American Geriatrics Society > 71 > 10 > 3322 - 3325

article

In Situ Reprogrammings of Splenic CD11b⁺ Cells by Nano‐Hypoxia to Promote Inflamed Damage Site‐Specific Angiogenesis (Adv. Funct. Mater. 32/2023)

Seyong Chung, Si Yeong Kim, Kyubae Lee, Sewoom Baek, more

Advanced Functional Materials > 33 > 32 > n/a - n/a

Splenic Filtering of Nanoparticles In article number 2302817, Hak‐Joon Sung, Seung Eun Yu, and co‐workers show that the inevitable splenic filtering of nanoparticles can be turned into an advantage. By loading a hypoxia‐mimetic agent onto liposomes, splenic CD11b⁺ cells undergo vasculogenic reprogramming, making them home inflamed sites and rescue damaged tissues under ischemia or resection.

article

In Situ Reprogrammings of Splenic CD11b⁺ Cells by Nano‐Hypoxia to Promote Inflamed Damage Site‐Specific Angiogenesis

Seyong Chung, Si Yeong Kim, Kyubae Lee, Sewoom Baek, more

Advanced Functional Materials > 33 > 32 > n/a - n/a

Clinical translation of nanoparticles is limited because of their short circulation time, which hampers targeting to prolong therapeutic effects. Angiogenesis is required to regenerate damaged sites under inflammation, and CD11b⁺ cells turn vasculogenic under hypoxia. As a turning‐point strategy to increase the circulation time, this study explores liposomal targeting of splenic CD11b⁺ cells, which...

article

Development and validation of the fall‐related injury risk in nursing homes (INJURE‐NH) prediction tool

Matthew S. Duprey, Andrew R. Zullo, Natalia A. Gouskova, Yoojin Lee, more

Journal of the American Geriatrics Society > 71 > 6 > 1851 - 1860

Background Existing models to predict fall‐related injuries (FRI) in nursing homes (NH) focus on hip fractures, yet hip fractures comprise less than half of all FRIs. We developed and validated a series of models to predict the absolute risk of FRIs in NH residents. Methods Retrospective cohort study of long‐stay US NH residents (≥100 days in the same facility) between January 1, 2016 and December...

article

Prevalence of Mutations in Mendelian Stroke Genes in Early Onset Stroke Patients

Hong‐Kyun Park, Keon‐Joo Lee, Jong‐Moo Park, Kyusik Kang, more

Annals of Neurology > 93 > 4 > 768 - 782

Objective Heritability of stroke is assumed not to be low, especially in the young stroke population. However, most genetic studies have been performed in highly selected patients with typical clinical or neuroimaging characteristics. We investigated the prevalence of 15 Mendelian stroke genes and explored the relationships between variants and the clinical and neuroimaging characteristics in a large,...

article

Restricted mean survival time versus conventional effect summary for treatment decision‐making: A mixed‐methods study

Sandra M. Shi, Jennifer A. Palmer, Natalie Newmeyer, Danette Carroll, more

Journal of the American Geriatrics Society > 71 > 2 > 528 - 537

Background Treatment effect is typically summarized in terms of relative risk reduction or number needed to treat (“conventional effect summary”). Restricted mean survival time (RMST) summarizes treatment effect in terms of a gain or loss in event‐free days. Older adults' preference between the two effect summary measures has not been studied. Methods We conducted a mixed methods study using a...

article

Feasibility of implementing a telephone‐based frailty assessment

Stephanie Denise M. Sison, Natalie Newmeyer, Karla Tejada Arias, Racheli Schoenburg, more

Journal of the American Geriatrics Society > 70 > 12 > 3610 - 3619

Background Despite the growing literature on the importance of identifying and managing frailty, its assessment has been limited in clinical settings. With the goal of integrating frailty assessment into routine clinical practice, this quality improvement project aimed to determine the feasibility, acceptability, and utility of administering a telephone‐based frailty assessment. Methods Between...

article

Predictors of long‐term medication adherence in stroke survivors: A multicentre, prospective, longitudinal study

Sung‐Hee Yoo, Gye‐Gyoung Kim, Sung Reul Kim, Man‐Seok Park, more

Journal of Clinical Nursing > 32 > 1-2 > 58 - 70

Background Although the optimal use of prescribed medications for stroke survivors is critical for preventing secondary stroke, longitudinal observations of the natural course of medication persistence and adherence in Korean stroke survivors are rare. Furthermore, studies are needed to identify strong predictors influencing medication adherence and to determine whether these predictors change over...

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INFONA - science communication portal

Search results for: Dae-Hyun Kim

Nano/microgroove zirconium‐doped lanthanum oxide film with self‐aligned molecules for liquid crystal device application

Use of chronic care management service among Medicare beneficiaries in 2015–2019

Artificial Vasa‐Vasorum Serves as an On‐Site Regenerative Promoter of Cell‐Free Vascular Grafting

Impact of peri‐operative frailty and operative stress on post‐discharge mortality, readmission and days at home in Medicare beneficiaries

Comparative safety and cardiovascular effectiveness of sodium‐glucose cotransporter‐2 inhibitors and glucagon‐like peptide‐1 receptor agonists in nursing homes

Utilization of transitional care management service among Medicare beneficiaries at high risk of readmission

Efficacy of Endovascular Thrombectomy in Acute Basilar Artery Occlusion with Low PC‐ASPECTS: A Nationwide Prospective Registry‐Based Study

Trends in use of antipsychotics and psychoactive drugs in older patients after major surgery

Construct validity of the electronic Veterans Affairs Frailty Index against clinician frailty assessment

Common non‐cardiovascular multimorbidity groupings and clinical outcomes in older adults with major cardiovascular disease

A crosswalk of commonly used frailty scales

Frailty and uptake of angiotensin receptor neprilysin inhibitor for heart failure with reduced ejection fraction

The median doses of beta‐blockers among older adults with heart failure with reduced ejection fraction

In Situ Reprogrammings of Splenic CD11b⁺ Cells by Nano‐Hypoxia to Promote Inflamed Damage Site‐Specific Angiogenesis (Adv. Funct. Mater. 32/2023)

In Situ Reprogrammings of Splenic CD11b⁺ Cells by Nano‐Hypoxia to Promote Inflamed Damage Site‐Specific Angiogenesis

Development and validation of the fall‐related injury risk in nursing homes (INJURE‐NH) prediction tool

Prevalence of Mutations in Mendelian Stroke Genes in Early Onset Stroke Patients

Restricted mean survival time versus conventional effect summary for treatment decision‐making: A mixed‐methods study

Feasibility of implementing a telephone‐based frailty assessment

Predictors of long‐term medication adherence in stroke survivors: A multicentre, prospective, longitudinal study

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