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Sacroiliac joint sepsis is more common than appreciated and therefore there is a potential for delay in diagnosis. The condition merits a high index of suspicion to be diagnosed. Prognosis is dependent upon prompt diagnosis and commencement of appropriate treatment. Antibiotic therapy alone is only occasionally successful in the treatment of osteomyelitis of the pelvic bones. Surgical intervention...
The systemic inflammatory response, as mediated by the cytokine network, is complex. While their presence is indispensable, it is often the excessive activity of either pro or anti-inflammatory cytokines that cause injury to the host and renders the patient immunocompromised. Furthermore, each cytokine must not be considered in isolation, but should be regarded as a part of a network of interacting...
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