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BACKGROUND
Ovarian metastases from colorectal cancer (OM‐CRC) often are unresponsive to chemotherapy and are associated with poor survival. To the authors' knowledge, the clinicopathologic and genomic predictors of OM‐CRC are poorly characterized and optimal clinical management remains unclear.
METHODS
Women with a histopathological diagnosis of OM‐CRC who were treated at Memorial Sloan Kettering...
BACKGROUNDToxicity from neoadjuvant chemoradiation therapy (NT) increases morbidity and limits therapeutic efficacy in patients with rectal cancer. The objective of this study was to determine whether specific polymorphisms in genes associated with rectal cancer response to NT were correlated with NT‐related toxicity.
METHODSOne hundred thirty‐two patients with locally advanced rectal cancer received...
BACKGROUND:The incidence of colon cancer increases with age, and colon cancer predominantly affects individuals >65 years old. However, there are limited data regarding clinical and pathologic factors, treatment characteristics, and survival of older patients with colon cancer. The objective of this study was to determine the effects of increasing age on colon cancer.
METHODS:Patients diagnosed...
BACKGROUND:It is unclear whether the administration of adjuvant chemotherapy improves survival in patients with American Joint Committee on Cancer (AJCC) stage II colon cancer.
METHODS:The authors used the State of California Cancer Surveillance Program (CSP) to assess patients ages 18 to 80 years with AJCC stage II colon cancer (ie, T3 or T4 and N0) who underwent surgical resection during 1991 and...
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