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What's known on the subject? and What does the study add?The loss of p27Kip1 correlates with poor prognosis in various human cancers, and was postulated as a biomarker in RCC. Up to now p27Kip1 analysis in RCC was focused on its nuclear localization.We confirmed higher p27Kip1 expression in the nucleus and cytoplasm of RCC and correlated high cytoplasmic p27Kip1 with an unfavourable clinic and a reduced...
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