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Dżdżownice posiadają silne, bardzo efektywnie funkcjonujące komórkowe i humoralne mechanizmy odpornościowe pozwalające przetrwać im w ich naturalnym, bogatym w patogeny środowisku. Z badań licznych zespołów wynika, że w tkankach dżdżownic występują białka, które wykazują między innymi właściwości bakteriostatyczne, cytolityczne, antyoksydacyjne oraz przeciwnowotworowe. Cytotoksyczne składniki (m.in...
This paper provides direct evidence that earthworm immune cells, coelomocytes, are exposed to bio-reactive quantities of metals within 3 days after dermal exposure, and that they respond by upregulating metallothionein (MT) and heat shock protein (HSP70, HSP72) expression. Indirect support for the hypothesis that coelomocytes are capable of trafficking metals was also obtained. Coelomocytes were expelled...
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