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In article number 2004615, Inge K. Herrmann and co‐workers present cathodoluminescence‐based color immunotargeting enabling the localization of individual proteins along with full ultrastructural context. Cathodoluminescence electron microscopy using nanocrystal‐based molecular probes gives access to true color electron microscopy with nanometric resolution and offers a new route to assess structure‐function...
The understanding of living systems and their building blocks relies on the assessment of structure–function relationships at the nanoscale. Although electron microscopy (EM) gives access to ultrastructural imaging with nanometric resolution, the unambiguous localization of specific molecules is challenging. An EM approach capable of localizing biomolecules with respect to the cellular ultrastructure...
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