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Aim
Presently, N‐hydroxy‐N′‐phenyloctanediamide (vorinostat) which is an effective histone deacetylase inhibitor, is being synthesized chemically. Hence, present study aims to develop an eco‐friendly approach for the synthesis of vorinostat from N′‐phenyloctanediamide through biotransformation.
Methods and Results
Using the amidase of Bacillus smithii IIIMB2907 in time course conversion and organic...
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