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The role of gap junction coupling in generation of carbachol-induced theta-like activity (TLA) in hippocampal formation (HPC) slices was investigated in this study. Two gap junction (GJ) blockers, carbenoxolone (100 μM) and quinine (100 μM), were tested. Both GJ blockers abolished cholinergically induced theta-like activity and related cell discharges. Abolishing effects were observed after 40-45...
The effect of different temperatures of ACSF (18-42 o C) on carbachol (CCH)-induced field potentials were examined in the present study. Two hundred and thirty one experiments were performed on hippocampal formation slices maintained in a gas-liquid interface chamber. All slices were perfused with 50 μM CCH. A recording electrode was positioned in the region of CA3c pyramidal cells. The experiments...
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