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The number of patients waiting for transplants has increased despite the constant growth of the number of transplants performed. This is the reason why the possibility of using animal organ donors is taken into consideration. Since 2002, the problems concerning xenotrasplantation have been investigated in Poland in the frame of the project: Application of trangenesis in genetic modification of pigs...
In the conducted study the possibility of using the transgenic pig kidneys for allogenic and heterogenic transplantation was evaluated with regards to the clinical context. There were 3 nontransgenic and 6 transgenic pig donors with a human α1.3-fukosylotransferase gene. The recipient of the kidneys were 6 nontransgenic and 3 transgenic pigs. The kidneys were heterotopic transplantated to intraperitoneal...
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