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We report on the first measurements of definitive depolarization to access gold nanorod (GNR) perturbation and visualize GNR diffusion, distribution and concentration ex vivo, in vitro and in vivo in biologically and medically relevant scenarios.
The goal of tissue engineering is to restore or replace the lost functions of diseased or damaged organs. Ideally, engineered tissues should provide nutrient transport, mechanical stability, coordination of multicellular processes, and a cellular microenvironment that promotes phenotypic stability. To achieve this goal, many engineered tissues require both macro- (∼cm) and micro- (∼ 100μm) scale architectural...
Liver tissue engineering aims to provide novel therapies for liver diseases and create effective tools for understanding fundamental aspects of liver biology and pathologic processes. Approaches range from bio-mimetic in vitro model systems of the liver to three-dimensional implantable constructs. Collectively, these cell-based approaches endeavor to replace or enhance organ transplantation, which...
This chapter contains sections titled:
Introduction
Cell‐Based Therapies for Liver Disease and Failure
In Vitro Hepatic Culture Models
Three‐Dimensional Hepatocellular Systems: Development of Implantable Therapeutic Constructs
Conclusion
References
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