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The complexation of allophane nanoparticles with cisplatin, cis-dichlorodiammineplatinum (II) (CDDP) to deliver platinum prodrug into cancer cells was investigated. Using human lung carcinoma (A549) cells, profound studies including cellular uptake (endocytosis) analysis of allophane nanoparticle, cell cycle arrest abilities and apoptosis induction profiles were discussed in detail. As well as the...
Clay minerals are mainly used around traditional cosmetics and industrial products, but currently their target application is continuously expanding into pharmaceutical industry and tissue engineering. To broaden the knowledge of in vitro cytotoxicity of allophane nanoparticles against human cancer cells, the cytotoxicity of both natural and synthetic allophane nanoparticles for cultured human alveolar...
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