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Purpose The purpose of this study was to synthesize biodegradable Gd-DTPA l-cystine bisamide copolymers (GCAC) as safe and effective, macromolecular contrast agents for magnetic resonance imaging (MRI) and to evaluate their biodegradability and efficacy in MR blood pool imaging in an animal model. Methods Three new biodegradable GCAC with different substituents at the cystine bisamide [R = H (GCAC),...
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