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To investigate the effects of a novel acrosome formation-associated factor (Afaf) on fertilization by its regulation of acrosomal exocytosis and endosomal trafficking.Controlled laboratory study.Institution-affiliated state key laboratory.ICR mice.Sperm penetration assay and in vitro fertilization experiment were performed to study the effects of the Afaf antibody on acrosome reaction and fertilization...
To investigate the effect of immunization with a DNA vaccine of testis-specific sodium-hydrogen exchanger (tsNHE) via oral feeding or nasal instillation on fertility in female mice and to look at its potential mechanism.Prospective, research study.Institution-affiliated research laboratory.Sexual mature BALB/c mice.Female mice immunized orally or nasally with the DNA vaccine at 2-week' intervals.Number...
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