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Background
Tacrolimus pharmacokinetics are influenced by age and CYP3A5 genotype with CYP3A5 expressors (CYP3A5*1/*1 or *1/*3) being fast metabolizers. However, the benefit of genotype‐guided dosing in pediatric solid organ transplantation has been understudied.
Objective
To determine whether age and CYP3A5 genotype‐guided starting dose of tacrolimus result in earlier attainment of therapeutic...
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