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In the present study we highlight recent applications of liquid beam desorption mass spectrometry for the analysis of biomolecules. The protonated macromolecules are desorbed from a 10μm thick liquid jet in vacuum with an IR laser pulse tuned in resonance with the OH stretch vibration of water. Cytochrome c, viscotoxin A3, synthetic analogues of DNA and nucleobase substituted β-peptides (PNA like...
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