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An outward current (I out ) was produced by stereoisomers of β-hydroxy-l-glutamic acid (l-BHGA), an l-glutamic acid (l-Glu) derivative, applied by brief pneumatic pressure ejection on an identifiable neurone type, v-LCDN (ventral-left cerebral distinct neurone), of Achatina fulica Ferussac. However, l- and D-Glu were almost ineffective on this neurone type. The pharmacological...
The sensitivities of 22 giant neurone types of an African giant snail (Achatina fulica Ferussac) to threo-β-hydroxy-l-glutamic acid (threo-l-BHGA), a derivative of l-glutamic acid (l-Glu), applied by brief pneumatic pressure ejection, were examined under current clamp. The 5 neurone types were depolarized by this compound, whereas 2 were hyperpolarized. The 4 neurone types, PON (periodically oscillating...
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