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We report here a short enantioselective synthesis of Ozanimod, a potent modulator of the enzyme Sphingosine‐1‐phosphate receptor (S1PR), recently approved by FDA and EMA for the treatment of relapsing‐remitting multiple sclerosis. Amongst different synthetic approaches explored, we achieved the best result introducing the stereogenic centre in the last step through imine asymmetric transfer hydrogenation...
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